Studying Tumor Evolution & Therapy Response
Publications
Müller N, Lorenz C, Ostendorp J, Heisel F, Friese U, Cartolano M, Plenker D, Tumbrink HL, Heimsoeth A, Baedeker P, Weiss J, Ortiz-Cuaran S, Büttner R, Peifer M, Thomas RK, Sos ML, Berg J, Brägelmann J.
Cancer Research 2023
Malchers F, Nogova L, van Attekum M, Maas L, Brägelmann J, Bartenhagen C, Girard L, Bosco G, Dahmen I, Michels S, Weeden CE, Scheel AH, Meder L, Golfmann K, Schuldt P, Siemanowski J, Rehker J, Merkelbach-Bruse S, Gautschi O, Heuckmann J, Brambilla E, Asselin-Labat ML, Persigehl T, Minna J, Walczak H, Ullrich RT, Fischer M, Reinhardt HC, Wolf J, Büttner R, Peifer M, George J, Thomas RK.
Somatic ectodomain deletions of FGFR1 in squamous cell lung cancer.
Journal of Clinical Investigations 2023
Arolt C, Dugan M, Wild R, Richartz V, Holz B, Scheel AH, Brägelmann J, Wagener-Ryczek S, Merkelbach-Bruse S, Wolf J, Buettner R, Catanzariti L, Scheffler M, Hillmer AM.
Journal of Thoracic Oncology 2023
Glaser M, Rasokat A, Prang D, Nogova L, Wömpner C, Schmitz J, Bitter E, Terjung I, Eisert A, Fischer R, John F, Von Levetzow C, Michels S, Riedel R, Ruge L, Scharpenseel H, Siebolts U, Merkelbach-Bruse S, Buettner R, Brägelmann J, Wolf J, Scheffler M.
Lung Cancer 2023
2023
Borchmann S, Selenz C, Lohmann M, Ludwig H, Gassa A, Brägelmann J, Lohneis P, Meder L, Mattlener J, Breid S, Nill M, Fassunke J, Wisdom A, Compes A, Gathof B, Alakus H, Kirsch D, Hekmat K, Büttner R, Reinhardt HC, Hallek M, Ullrich RT.
Tripartite antigen-agnostic combination immunotherapy cures established poorly immunogenic tumors
Journal for Immunotherapy of Cancer 2022
Müller F, Lim JKM, Bebber CM, Seidel E, Tishina S, Dahlhaus A, Stroh J, Beck J, Yapici FI, Nakayama K, Torres Fernández L, Brägelmann J, Leprivier G, von Karstedt S.
Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation.
Cell Death & Differentiation 2022
Selenz C, Compes A, Nill M, Borchmann S, Odenthal M, Florin A, Brägelmann J, Büttner R, Meder L, Ullrich RT.
Cancers 2022
Lategahn J, Tumbrink H, Schultz-Fademrecht C Heimsoeth A, Werr L, Niggenaber J, Keul M, Parmaksiz F, Baumann M, Menninger S, Zent E, Landel I, Weisner J, Jeyakumar K, Heyden L, Russ N, Müller F Lorenz C, Brägelmann J, Spille I, Grabe T, Müller M, Heuckmann J, Klebl B, Nussbaumer P, Sos ML, Rauh D.
Journal of Medicinal Chemistry 2022
2022
Schaufler D", Ast D",Tumbrink H, Abedpour N, Maas L, Schwäbe A, Spille I, Lennartz S, Fassunke J, Aldea M, Besse B, Planchard D, Nogova L, Michels S, Kobe C, Persigehl T, Westphal T, Koleczko S, Fischer R, Weber J, Altmüller J, Thomas R, Merkelbach-Bruse S, Gautschi O, Mezquita L, Büttner R, Wolf J, Peifer M, Brägelmann J*, Scheffler M*, Sos M*.
Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer.
npj Precision Oncology
(*co-corresponding authors, "contributed equally)
Brägelmann J*", Lorenz C", Borchmann S, Nishii K, Wegner J, Meder L, Ostendorp J, Ast D, Heimsoeth A, Nakasuka T, Hirabae A, Okawa S, Dammert M, Plenker D, Klein S, Lohneis P, Gu J, Godfrey L, Forster J, Trajkovic-Arsic M, Zillinger T, Haarmann M, Quaas A, Lennartz S, Schmiel M, D’Rozario J, Thomas E, Li H, Schmitt CA, George J, Thomas RK, von Karstedt S, Hartmann G, Büttner R, Ullrich RT, Siveke JT, Ohashi K, Schlee M, Sos M*.
Nature Communications
(*co-corresponding authors, "contributed equally)
Brägelmann J, Barahona Ponce C, Marcelain K, Roessler S, Goeppert B, Gallegos I, Colombo A, Sanhueza V, Morales E, Rivera MT, de Toro G, Ortega A, Müller B, Gabler F, Scherer D, Waldenberger M, Reischl E, Boekstegers F, Garate Calderon V, Umu SU, Rounge TB, Popanda O, Lorenzo Bermejo J.
Hepatology 2020
Watermann C, Pasternack H, Idel C, Ribbat-Idel J, Brägelmann J, Kuppler P, Offermann A, Jonigk D, Kühnel M, Schröck A, Dreyer E, Rosero C, Nathansen N, Dubrovska A, Tharun L, Kirfel J, Wollenberg B, Perner S, Krupar R.
Clinical Cancer Research 2021
2021
Paulsen F, Idel C, Ribbat-Idel J, Kuppler P, Klapper L, Rades D, Bruchhage K, Wollenberg B, Brägelmann J, Perner S, Offermann A.
CDK19 as a Potential HPV-Independent Biomarker for Recurrent Disease in HNSCC
IJMS 2020
Becker F, Joerg V, Hupe MC, Roth D, Krupar R, Lubczyk V, Kuefer R, Sailer V, Duensing S, Kirfel J, Merseburger AS, Brägelmann J, Perner S, Offermann A.
Increased mediator complex subunit CDK19 expression associates with aggressive prostate cancer
International Journal of Cancer 2020
2020
Dammert MA*, Brägelmann J*, Olsen RR*, Böhm S*, Monhasery N, Whitney CP, Chalishazar MD, Tumbrink HL, Guthrie MR, Klein S, Ireland AS, Ryan J, Schmitt A, Marx A, Ozretic L, Castiglione R, Lorenz C, Jachimowicz RD, Wolf E, Thomas RK, Poirier JT, Büttner R, Sen T, Byers LA, Reinhardt HC, Letai A, Oliver TG, Sos ML.
Nature Communications 2020
(*contributed equally)
Scheffler M, Ihle MA, Hein R, Merkelbach-Bruse S, Schee Al, Siemanowski J, Brägelmann J, Kron A, Abedpour N, Ueckeroth F, Schüller M, Koleczko S, Michels S, Fassunke J, Pasternack H, Heydt C, Serke M, Fischer R, Schulte W, Gerigk U, Nogova L, Ko YD, Abdulla DSY, Riedel R, Kambartel K, Lorenz J, Sauerland I, Randerath W, Kaminsky B, Hagmeyer L, Grohé C, Eisert A, Frank R, Gogl L, Schaepers C, Holzem A, Hellmich M, Thomas RK, Peifer M, Sos ML, Büttner R, Wolf J.
K-ras Mutation Subtypes in NSCLC and Associated Co-occuring Mutations in Other Oncogenic Pathways
Journal of Thoracic Oncology 2019
Michels S, Heydt C, van Veggel B, Deschler-Baier B, Pardo N, Monkhorst K, Rüsseler V, Stratmann J, Griesinger F, Steinhauser S, Kostenko A, Diebold J, Fassunke J, Fischer R, Engel-Riedel W, Gautschi O, Geissinger E, Haneder S, Ihle MA, Kopp HG, de Langen AJ, Martinez-Marti A, Nogova L, Persigehl T, Plenker D, Puesken M, Rodermann E, Rosenwald A, Scheel AH, Scheffler M, Spengler W, Seggewiss-Bernhardt R, Brägelmann J, Sebastian M, Vrugt B, Hellmich M, Sos ML, Heukamp LC, Felip E, Merkelbach-Bruse S, Smit EF, Büttner R, Wolf J.
JCO Precision Oncology 2019
2019
Johannes Brägelmann*, Justo Lorenzo Bermejo*
Briefing in Bioinformatics 2018
(*co-corresponding authors)
Nature Communications 2018
2018
Brägelmann J*, Dammert MA*, Dietlein F*, Heuckmann JM*, Choidas A*, Böhm S, Richters S, Basu D, Tischler V, Lorenz C, Habenberger P, Fang Z, Ortiz-Cuaran S, Leenders F, Eickhoff J, Koch U, Getlik M, Termathe M, Sallouh M, Greff Z, Varga Z, Balke-Want H, French CA, Peifer M, Reinhardt HC, Őrfi L, Kéri G, Ansén S, Heukamp L, Büttner R, Rauh D, Klebl B, Thomas RK, Sos ML.
Cell Reports 2017
Mollaoglu G*, Guthrie MR*, Böhm S*, Brägelmann J*, Can I, Ballieu PM, Marx A, George J, Heinen C, Chalishazar MD, Cheng H, Ireland AS, Denning KE, Mukhopadhyay A, Vahrenkamp JM, Berrett KC, Mosbruger TL, Wang J, Kohan JL, Salama ME, Witt BL, Peifer M, Thomas RK, Gertz J, Johnson JE, Gazdar AF, Wechsler-Reya RJ, Sos ML, Oliver TG.
Cancer Cell 2017
(*contributed equally)
Brägelmann J, Klümper N, Offermann A, von Mässenhausen A, Böhm D, Deng M, Queisser A, Sanders C, Syring I, Merseburger AS, Vogel W, Sievers E, Vlasic I, Carlsson J, Andrén O, Brossart P, Duensing S, Svensson MA, Shaikhibrahim Z, Kirfel J, Perner S.
Clinical Cancer Research 2017